Tuesday, June 7, 2011

Perinatal pitocin as an early ADHD biomarker: neurodevelopmental risk? (NBCI)

NBCI published results of new research of ADHD ( Attention Deficit Hyperactivity disorder) which ocurence is on rise word wide. Following study investigated relation between ADHD and Pitocin, which is synthetic hormone Oxytocin which is widly used for induction of labor. Study was conducted on small group, 172 children and revealed increased rate of ADHD in kids where pitocin was used in labor. Further studies are needed to generalize the results. 


Colorado State University, Fort Collins, CO, USA. Lisa.Kurth@ColoState.edu.


Objective: To investigate a potential relationship between coincidental increases in perinatal Pitocin usage and subsequent childhood ADHD onset in an attempt to isolate a specific risk factor as an early biomarker of this neurodevelopmental disorder.

 Method: Maternal labor/delivery and corresponding childbirth records of 172 regionally diverse, heterogeneous children, ages 3 to 25, were examined with respect to 21 potential predictors of later ADHD onset, including 17 selected obstetric complications, familial ADHD incidence, and gender. ADHD diagnosis and history of perinatal Pitocin exposure distinguished groups for comparison. 
Results: Results revealed a strong predictive relationship between perinatal Pitocin exposure and subsequent childhood ADHD onset (occurring in 67.1% of perinatal Pitocin cases vs. 35.6% in nonexposure cases, χ(2) = 16.99, p < .001). Fetal exposure time, gestation length, and labor length also demonstrated predictive power, albeit significantly lower. Conclusion: The findings warrant further investigation into the potential link between perinatal Pitocin exposure and subsequent ADHD diagnosis.

[PubMed - in process]

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